Hybrid Approaches in structure prediction

This is a cost effective approach for determining the protein structure. The computational prediction methods, such as initiating fragment assembly, advanced fold recognition, composite approaches, and molecular docking are regularly applied in recent times to expand our understanding of protein structures. Hybrid approach is a channel to overcome these disadvantages, by incorporating limited experimental measurements, reliable structures can be computed and unlikely predictions are eliminated. The current researches are showing great interest in this method of approach.

  • NMR structures
  • Hybrid of experimental methods
  • Hybrid of computational methods
  • Hybrid approaches in complementing high-resolution structural biology
  • Determining protein complex structures
  • Bottom-up integration of atomic detail crystallography

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