Structural Biology

Hybrid Approaches in Structure Prediction

This is a price effective approach for determining the protein structure. The computational prediction methods, like initiating fragment assembly, advanced fold recognition, composite approaches, and molecular docking are regularly applied in recent times to expand our understanding of protein structures. Hybrid approach may be a channel to beat these disadvantages, by incorporating limited experimental measurements, reliable structures are often computed, and unlikely predictions are eliminated. The present researches are showing great interest during this method of approach.

• NMR structures
• Hybrid of experimental methods
• Hybrid of computational methods
• Hybrid approaches in complementing high-resolution structural biology
• Determining protein complex structures
• Bottom-up integration of atomic detail crystallography