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Theme: An Insight into Every Dimension of Advanced Structural Biology Research

Structural Biology 2021

structural Biology

Renowned Speakers

Karim Fahmy
University of Dresden
Germany

Henry M Sobell
University of Rochester
USA

Niklaus Ammans
Bern University
Switzerland

Yawen Bai
National Institutes of Health
USA

Amelia Pilar Rauter
University of Libson
Portugal

Holland Cheng
University of California
USA

Henry M. Sobell
University of Rochester
USA

Yuri L.Lyubchenko
University of Nebraska
USA

Joachim Krebs
Max Planck Institute Germany
Germany

Michael Hennig
CEO LeadXpro AG
Switzerland

Magnus S Magnusson
University of Iceland
Iceland

Structural Biology 2021

On behalf of Scientific Organising Committee we are overwhelmed to welcome all the interested participants to attend 20th International Conference on Structural Biology during October 18-19, 2021, Webinar.

The conference is going to be organized on the theme:An Insight into Every Dimension of Advanced Structural Biology Research. This Biochemistry Congress goes to be the most important and most promising international conference that specifically focuses on the Structural Biology by bringing all renowned researchers under one roof. this is often a 3 day multidisciplinary meeting covering all aspects of novel research and contributions within the field of structural biology and biophysics.

• Commendable talks by the first-string of the worldwide scientific community.
• Sterling workshop sessions.
• Remarkable Awards and Global Recognition to meritorious Researchers.
• Global Networking with 50+ Countries.
• Novel Techniques to profit Your Research.
• Global Business and Networking Opportunities.
• Exquisite platform for exhibiting your by-products and International Sponsorship

Young Scientist Benefits

Our conferences provide best Platform for your research through oral presentations.
Share the ideas with both eminent researchers and mentors.
Young Scientist Award reorganization certificate and memento to the winners
Young Scientists will get appropriate and timely information by this Forum.
Platform for collaboration among young researchers for better development
Award should motivate participants to strive to understand their full potential which could successively be beneficial to the sector as whole.

Deadline for Registrations:
Speaker Registration €249
Delegate Registration €299

Track 1: Structural Biology

Structural Biology is that the branch of biology which embarks the importance of Biochemistry and Biophysics within the molecular structure of biological macromolecules. It also provides information about the effect of structural alterations of macromolecules on their function. This process of determination of structures of proteins, nucleic acids may take years because the shape, size and assemblies of those molecules could also be altering the function.

Structural modifications in nucleic acids
Biological system
Biochemistry
Alternations in Protein Structure

Related Societies:

American Society for Cell Biology, American Society for Biochemistry and Molecular Biology, Association of South-Eastern Biologists, Federation of European Biochemical Societies, Royal Society of Biology, Society for Experimental Biology, International Society for Computational Biology, Society for Molecular Biology and Evolution, American Crystallographic Association, Belgian Society of Biochemistry and Molecular Biology, International Mass Spectrometry Foundation, International Union of Crystallography, European Society of Human Genetics, European Proteomics Association, European Molecular Biology Organization, African Society for Bioinformatics and Computational Biology, American Mass Spectrometry Society, Australasian Proteomics Society, Austrian Proteomics Society.

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Track 2: Proteomics and Genomics

Proteomics is that the newest and therefore the most discussed topic within the field of Structural Biology. It deals with determining the structure and performance of proteins- the building blocks of the physical body . It found its importance after the introduction of the Human Genome Project. Almost every process that happens in our cells – from the metabolization of straightforward sugar to the division of cells – depends on proteins for smooth operation. Genomics is that the study of structure, working, mapping and alteration of genomes. the whole arrangement of DNA- the knowledge center of our body is understood as genomics. Proteomics and Genomics are interrelated. Proteomics involve the study of structural determination of the body whereas Genomics involve the study of genetic makeup of the body.

Chemical & single cell proteomics
Molecular and cellular proteomics
Expression proteomics
Quantitative proteomics
Post-translational modifications & signal transduction
Cancer Genomics
Clinical Genomics
Comparative Genomics
Functional Genomics

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Track 3: Biochemistry and Biophysics

Biochemistry is that the study of chemical processes happening inside the physical body .Recently this subject has found its importance within the biological world because it has found its importance altogether fields of bioscience and biology. By controlling information flow through biochemical signaling and therefore the flow of energy through metabolism, biochemical processes produce to the complexity of life. Its main focus is to know how biological molecules produce to the processes that occur within living cells.

Biophysicsis that the trending topic within the field of biology. It relates physics and biology. In other words, it signifies how traditional physical methods are wont to study the biological phenomena inside the physical body . Biophysical research shares significant overlap with biochemistry, biology , chemistry , physiology, nanotechnology, bioengineering, computational biology, biomechanics and systems biology.

Systems Biology
Metabolomics
Biomolecules
Biophysical approaches to cell biology
Membrane Biophysics
Computational and theoretical Biophysics

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Track 4: Molecular Biology

Molecular Biology may be a vast topic which deals with the structure and performance of macromolecules. it's usually combined with techniques of Genetics and Biochemistry. Till 2000, genetics was the sub-field of biology.Since biology is usually quantitative it’s in edge with computational biology and bioinformatics. Other zones of Biology focus directly or indirectly on molecules, whereas developmental biology and cell biology focus directly, while phylogenetic and evolutionary biology focus indirectly. Genetics deals with study of mutants and its comparison with the wild type (normal phenotype).

Genetics
Cell Biology
Developmental Biology
Gene Expression

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Track 5: 3-D Structure Determination

Biomolecules are very small to ascertain intimately even by most cutting-edge light microscopes. The methods that the structural biologists use to work out their structures generally involve the measurements on huge numbers of identical molecules at an equivalent time. a number of the simplest methods include X-ray crystallography, cryo-electron microscopy and nuclear resonance aside from these methods there are many additional methods through which 3-D Structure Determination are often done.

X-ray crystallography
Nuclear Magnetic Resonances
Cryo-Electron Microscopy
Mass spectroscopy
Dual polarisation interferometry
Multi-angle light scattering Technique
Ultra-fast laser spectroscopy

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Track 6: Computational Approach in Structural Biology

Computational approaches are a boon for structural biology. These methods use the concepts of bioinformatics to work out the structure of macromolecules. generally , the structure of molecules is decided by experimental methods is both time intense and price effective. to beat these constraints, computational approaches like ab-initio modelling, homology modelling and threading method are used.

Homology modelling
Ab-initio method
Threading
Discoveries through computational approaches

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Track 7: Molecular Modelling and Dynamics

Molecular modelling involves the hypothetical and computational procedures which are wont to mimic the behaviour of macromolecules. Molecular Modelling techniques are utilized in various fields a number of which are drug design, computational chemistry, materials science and computational biology. These methods are used for studying and understanding the properties of the molecules. one among the main applications of molecular modelling is molecular simulation. this is often the technique which uses powerful lculatiocomputers to simulate the interactions between atoms and to know the properties of materials. Such simulations involve methods that range from very detailed quantum mechanical cans on atoms to coarse-grained classical dynamics of huge groups of molecules on a timescale of milliseconds or longer.

Molecular dynamics (MD) deals with the study of physical movements of the atoms and molecules using simulation method, so it's mentioned together of the sort of N-body simulation. The atoms and molecules are allowed to interact for a hard and fast period of your time , giving a view of the dynamic evolution of the system. The trajectories of atoms and molecules are commonly determined by solving them numerically using Newton’s equations of motion for a gaggle of collaborating particles. The forces between the particles and their potential energies are calculated using inter-atomic potentials or molecular mechanics force fields. Steered molecular dynamics (SMD)

Potentials in ab-initio methods
Hybrid QM/MM
Protein folding
Enzyme catalysis
Protein stability
Molecular recognition of proteins
DNA and membrane complexes

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Track 8: Drug Designing and Biomarkers

A biomarker is an attribute which will be studied as an indicator of pathogenic and biological operation along side pharmacological retort to a therapeutic involvement. They indicate either normal or diseased activity within the body. Biomarkers are specific molecules, genes, gene products, hormones, cells or enzymes.

Drug Designing is an ingenious process to seek out new medication centred on the knowledge of biological target. Drug is most ordinarily a little molecule that inhibits or activates the function of a biomolecule, which successively outcomes during a therapeutic benefit to the patient. Drug design commonly but not essentially relies on computational techniques. this sort of modelling is usually mentioned to as computer-aided drug design.

Drug targets
Ligand-based design
Structure-based design
Computer-aided drug design
Scoring functions

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Track 9: Gene regulation and Cell Signalling

Signalling is that the process through which the cells communicate with one another . they're often secreted from the cell and released into the extracellular space. Regulation of organic phenomenon comprises a comprehensive range of mechanisms that are employed by cells to manage the assembly of specific gene products, and is familiarly termed as gene regulation. Sophisticated programs of organic phenomenon are extensively observed in biology, for instance to trigger developmental pathways, adapt to new food sources, or answer environmental stimuli.

G-protein-coupled receptor
Adrenergic receptor
Protein crystallography
Protein structure

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Tracks 10: Structural Enzymology

Structural Enzymology play an important role in signalling the cellular and metabolic pathways. Research works are happening to spot , how the enzymes function at molecular and atomic level by combining the fashionable and Structural Biology

Protein engineering
Protein prenylation techniques
Steady state kinetics
Calorimetric methods
Chemical analysis

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Track 11: Sequencing Analysis

Sequence analysis are often explained as a process of exposing DNA, RNA or peptide sequence to a good range of analytical methods so as to know its structure, function and evolution. The methods include sequence alignment and biological databases. Synergistic use of 3-D Structure Determination and deep sequencing is completed to understand the effect of personalized medicine. The usage of sequence analysis in Structural Biology will pave the thanks to new methods which may be utilized to work out the structure of molecules.

Profile comparison
Sequence assembly
Gene prediction
Deep sequencing for protein structure determination
Complementary Methods
Deep sequencing for cancer studies
Deep sequencing of HIV

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Track 12: Hybrid approaches in Structure prediction

This is a price effective approach for determining the protein structure. The computational prediction methods, like initiating fragment assembly, advanced fold recognition, composite approaches, and molecular docking are regularly applied in recent times to expand our understanding of protein structures. Hybrid approach may be a channel to beat these disadvantages, by incorporating limited experimental measurements, reliable structures are often computed, and unlikely predictions are eliminated. the present researches are showing great interest during this method of approach.

NMR structures
Hybrid of experimental methods
Hybrid of computational methods
Hybrid approaches in complementing high-resolution structural biology
Determining protein complex structures
Bottom-up integration of atomic detail crystallography

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Track 13: Structural Bioinformatics

Structural bioinformatics is an exceptionally cost-effective solution for protein structure determination. Purely computational prediction methods, like initially fragment assembly, advanced fold recognition, composite approaches, and molecular docking are regularly applied today to increase our understanding of protein structures. However, predicted structures aren't given an equivalent reliance as their experimental complements. Hybrid approaches are a way to beat these limitations; by incorporating limited experimental measurements, reliable structures are often computed, and unlikely predictions eliminated. Hybrid approaches cash in of knowledge derived from a good range of various biophysical and biochemical methods. These methods are of growing interest in current researches of Structural Biology.

Genome Mapping
Translational Medicine
Protein Modelling
Epigenomic data analysis
Computational Neuroscience
Mathematical Techniques

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Track 14: Frontiers in Structural Biology

The main focus of a Structural Biology is protein structure determination and drug design. Protein plays a crucial role in physical body . Living things wouldn't exist without proteins. The proteins are usually involved altogether sorts of expressions of the living organism. Most of the proteins are evolved in providing structure to the cell while the others tend to bin and carry vital molecules during the body. Some proteins are involved in biochemical reactions within the body which are termed as enzymes. Others are involved in muscle contractions and immunity. Structure determination of proteins has always been a challenging filed. The complex areas within the field include viruses, pathogens, membrane proteins and signalling pathways. Novel progressions are being wiped out the arenas of nano-patterning and multi-scale modelling of cell signalling proteins.

Membrane proteins
Pathogens and viruses
Nano patterning
Macromolecular designing

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Track 15: Structural Biology in Cancer Research

The main aim of integrating Structural Biology data into cancer research is to style and find out novel and effective drugs to cure the disease. Structural biology combined with molecular modelling mainly aims at drug designing. Consequently, variety of Structural Biologists are conducting cancer research, to speed-up the method of understanding the mechanism of biomolecules so as to enhance the newer cancer therapies.

Major a part of research is being administered within the area of cancer. the most aim is to style and find out novel and effective drugs to cure the disease. Structural Biology combined with molecular modelling mainly aims at drug designing. Subsequently, numerous team leaders in Structural biology perform cancer research to accelerate the exploitation of molecular understanding of biomolecules within the advancement of novel cancer therapies.

Cancer Systems Biology
Tumorigenesis
Cancer Heterogeneity
Epidemiology
Statistical and Mechanistic Modelling of Signalling Networks

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Track 16: Molecular biology techniques

Molecular biology techniques are utilized in biology , biochemistry and genetics for the analysis of DNA, RNA and protein. Molecular cloning is that the widely used molecular technique. the various methods in biology are Haemocytometer cell counter, restriction endonuclease digestion, DNA ligation, transfection, western blot, plasmid purification, electroporation, heat shock method and ELISA.

DNA sequencing‎
Gene delivery
Microarrays‎

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Track 17: Structural Biology Databases

A database is an organised collection of knowledge . As a results of enormous research which is being wiped out Structural biology massive data has been produced. so as to assemble the info during a catalogued manner, Bioinformatics databases are used. Various databases are created to store biological data, like sequence databases, structure databases, signalling pathway databases, etc.

A database may be a structured collection of knowledge . within the field of Structural Biologyy enormous research is being done and as a result massive data is being produced. so as to pile the info in an organized manner, bioinformatics databases are used. Various databases are created to store biological data, like sequence databases, structure databases, signalling pathway databases, etc. within the field of structural biology, the mainly used databases are Protein Data Bank (PDB), microscopy Data Bank, Protein Structure Classification Database (CATH) and Structural Classification of Protein (SCOP).

Classification of structural database
Classification of protein structure
Protein structure classification database
Protein data bank
Electron microscopy data bank

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Track 18: Advancements in structural Biology

Structural Biology is one among the progressing fields. within the course of your time many developments are happening . Huge numbers of solved structures have exaggerated rapidly. the sector of drug design and drug discovery has been advanced. Functional annotations are another field where progressions are rapidly evolving. Alterations so as to enhance the effectiveness of prevailing tools also can be noted. Remarkable advances are made within the areas of technical imaging and advancement of hybrid methods to know the structure and performance of proteins.

Advances in Drug Design
Advances in Tool Development
Advances in Imaging Technologies

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Assets apportioned to Structural Biology Research:

The Higher Education Funding Council for European nation (HEFCE), the office responsible for the circulation of practically £8 billion (US$11.3 billion) of administration assets for the instructive year 2009–10, divulged conditional subsidizing distributions for investigation (£1.57 billion) and instructing (£4.78 billion). Office spends or so $65 million consistently for super atom structure assurance. Australia awards cost $7.4 million for fourteen national comes supporting the development of the therapeutic innovations, biotechnologies and endorsed drugs division. The Ministry of Education, Culture, Sports, Science and Technology (MEXT)— the main authority body in organizing and subsidizing science and innovation activities in Japan—mentioned US$11.1 billion for science and innovation installment in its anticipated spending plan. National Institute on propensity (NIDA), bar investigation, has supported $358.1 million of every 2015. The territory of American state has purportedly put with $10-12 million in direct disease examination every year, while the National Cancer Institute (NCI) among the U. S. has supposedly pay $4.8 to $5.2 billion every year on malignant growth examination and treatment advancement. With the ongoing solicitation for applications, the NIGMS hopes to help 3 to 6 monstrous investigation focus' at evaluation of up to $3 million for every middle

Market Value of Structural Biology:

The principle examination promote is depended upon to accomplish USD 41.34 Billion by 2021 from USD 28.66 Billion out of 2016, at a CAGR of 7.6% from 2016 to 2021. The principle contemplations driving the improvement of this market are the creating biotechnology and biopharmaceutical adventures, introduction of creatively moved cell examination instruments, extending event of powerful and endless sicknesses and rising number of patients encountering ailment, and growing theories from various government affiliations and life sciences associations for cell science inspect works out.

The market is basically controlled by the growing exploration financing for helper science from governments and private theorists, creating enthusiasm for novel drug diagram and tweaked arrangement in the U.S. in addition, Europe, and the growing necessity for toxicology testing. The closeness of endless equipment makers has contributed on a very basic level toward the North American and European assistant science/sedate publicizes. In any case, the Asia-Pacific district addresses a vital improvement open entryway for the helper science/quiet market during the check time of 2014 to 2019. The APAC grandstand is depended upon to create at a CAGR of 23% during the measure time allotment. The improvement in this market is driven by the creating pharmaceutical and biotechnology adventures. The overall essential science promotes was regarded at $565 million out of 2014 and is depended upon to create at a CAGR of 30% from 2014 to 2019.

Target audience:

Directors/Managers & Business Delegates, Director of Laboratories, Universities, Industries, Investigators, Post-Doctoral Fellows, Research and Diagnostic Laboratories, Clinical Fellows, Research Scholars, Students, Biomedical Research companies. Rise in the number of clinical trials, toxicological studies, and health awareness for nutritional products, rapid growth of structural biology analytical instruments, software, and solutions, implementing the methods of Structural Biology will help in the growth and development of the pharmaceutical company.

Major Structural Biology Related Associations around the Globe:

Biophysical Society

American Society for Biochemistry and Molecular Biology

Czech Society for Structural Biology

American Chemical Society

New England Structural Biology Association

The Protein Society

American Crystallographic Association

International Union of Crystallography

British Crystallographic Association

European Crystallographic Association

Hellenic Crystallographic Association

Bioinformatics society of India

International Society for Computational Biology

South African Crystallographic Society

Why to attend?

Those who want to meet the market targets by introducing the recent business reports in structural biology and also drug designing, which manifests the increased growth in pharmaceutical industry. As Structural Biology is focused on determination of the structure based on methods such as X-ray crystallography, Computational approaches for structure prediction, NMR studies, drug designing. The companies dealing with analytical instruments and software will have a great opportunity in these fields. Also many upcoming students and researchers can benefit themselves by participating in world class International workshops, symposia during the conference which will be conducted by experts in the respective fields.

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Conference Date	October 18-19, 2021
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