18^th International Conference on Structural Biology October 14-16, 2019 London, UK

Henry M. Sobell completed his studies at Brooklyn Technical High School (1948-1952), Columbia College (1952-1956), and the University of Virginia School of Medicine (1956-1960). Instead of practicing clinical medicine, he then went to the Massachusetts Institute of Technology (MIT) to join Professor Alexander Rich in the Department of Biology (1960-1965), where, as a Helen Hay Whitney Postdoctoral Fellow, he learned the technique of single crystal X-ray analysis. He then joined the Chemistry Department at the University of Rochester, having been subsequently jointly appointed to both the Chemistry and Molecular Biophysics departments (the latter at the University of Rochester School of Medicine and Dentistry), becoming a full tenured Professor in both departments (1965-1993). He is now retired and living in the Adirondacks in New York, USA.

Structural Biology

Yuri L Lyubchenko is the Professor of Pharmaceutical Sciences at the University of Nebraska Medical Center, Omaha, NE, USA. His research focuses on understanding fundamental mechanisms underlying health and disease, which are key to developing new and more effective diagnostics and medications. This primarily basic research allows him not only to identify new drug targets for small molecule drugs, it also leads to development of the nanotools and methods to discover novel approaches for diagnostic, treatment and disease prevention and to more rapidly determine their efficacy at the molecular level.

Single molecule Structural Biology, CryoEM

Dr. Joachim Krebs received his PhD from the University of Tübingen, Germany. He spent 2 years as a postdoctoral fellow with Prof. R.J.P.Williams at the University of Oxford, UK. In 1977 he accepted a position at the Institute of Biochemistry at the ETH in Zurich, Switzerland. In his Lab he focused his research on the structure-function relationship of calcium binding- and transporting proteins He has authored, coauthored, and edited numerous articles in international journals and books in the field of calcium biochemistry and calcium signaling. After his retirement from the ETH he continued his research at the Department of NMR based Structural Biology of the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany. Recently, he edited the book “Calcium: A Matter of Life or Death”, published by Elsevier in 2007. He is also on the Editorial Board of BBA Molecular Cell Research and a Section Editor of Archives of Biochemistry and Biophysics.

Biophysics, Biochemistry

Michael Hennig studied Physics and Biochemistry and received the Ph.D. in structural biology at EMBL Hamburg, and the Charité, Humboldt University Berlin, Germany. It followed two years postdoc work at the Biozentrum, University of Basel, Switzerland. He is author of more than 75 scientific peer reviewed paper and, since 2011, guest professor in structural biology at the University of Basel. From 1995 he worked 20 years in pharmaceutical industry at Roche, Basel, Switzerland in various positions and finally Global Head and Principle Leader of discovery technologies with responsibility for structure based drug discovery, protein science, assay development and HTS, corporate compound library, stem cell platform analytical methods. In 2015, he co-founded and is now CEO of leadXpro AG, a company dedicated to structure based drug discovery of membrane protein targets.

Structure based drug discovery, membrane protein structural biology, Synchrotron and Free Electron Laser, cryo-Electron Microscopy (EM), computational methods.